منابع مشابه
A Review Study: Using Stem Cells in Cartilage Regeneration and Tissue Engineering
Articular cartilage, the load-bearing tissue of the joint, has limited repair and regeneration ability. The scarcity of treatment modalities for large chondral defects has motivated researchers to engineer cartilage tissue constructs that can meet the functional demands of this tissue in vivo. Cartilage tissue engineering requires 3 components: cells, scaffold, and environment. ...
متن کاملImproved Artificial Cartilage Regeneration Tissue by Using Fibroin Sponge
INTRODUCTION There have been many attempts to repair full-thickness articular cartilage defects using tissue-engineering techniques, focusing particularly on the regeneration of high-strength cartilage. Unfortunately, the strength is insufficient for fixation of the grafted part on large defect of joint surface. Current focus in our laboratory has been placed on the development of a novel silk ...
متن کاملRegulation of lubricin for functional cartilage tissue regeneration: a review
Background Lubricin is chondrocyte-secreted glycoprotein that primarily conducts boundary lubrication between joint surfaces. Besides its cytoprotective function and extracellular matrix (ECM) attachment, lubricin is recommended as a novel biotherapeutic protein that restore functional articular cartilage. Likewise, malfunction of lubrication in damaged articular cartilage caused by complex and...
متن کاملTissue engineering strategies to study cartilage development, degeneration and regeneration.
Cartilage tissue engineering has primarily focused on the generation of grafts to repair cartilage defects due to traumatic injury and disease. However engineered cartilage tissues have also a strong scientific value as advanced 3D culture models. Here we first describe key aspects of embryonic chondrogenesis and possible cell sources/culture systems for in vitro cartilage generation. We then r...
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ژورنال
عنوان ژورنال: Osteoarthritis and Cartilage
سال: 2007
ISSN: 1063-4584
DOI: 10.1016/s1063-4584(07)61224-2